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Dr. Jairam Meena
Assistant Professor
Department of Pharmaceutical Engineering & Technology IIT(BHU)
Area of Interest: 
Vaccine Immunology and Immunotherapeutics

Post-Doctoral Fellow- University of Minnesota USA 
Ph.D- National Institute of Immunology, New Delhi
M.Pharm-Indian Institute of Technology (B.H.U.), Varanasi
B.Pharm-Mohanlal Sukhadiya University, Udaipur, Rajasthan


Vaccine Immunology-Vaccine development for infectious diseases, Glycoconjgate vaccine for T cell independent carbohydrate antigens, Adjuvants 
Antibody drug conjugates and immunotherapy 
Nanoparticle based drug delivery 
Recombinant protein antigen purification 

Papers Published 

Total Impact Factor-139.11
Average Impact Factor-6.32

1. Ahuja R, Shelly A, Meena J, Singh M, Sehgal D, Panda AK. Enhanced immunogenicity of recombinant pneumococcal protein delivered using thermostable polymer particles. Materialstoday Communications. 2022: 103894. IF: 3.66

2. Meena J*, Singhvi P, Srichandan S, Dandotiya J, Verma J, Ahuja R, Panwar P, Wani TQ, Khatri R, Siddiqui G, Gupta A, Samal S, Panda AK. RBD decorated PLA nanoparticle admixture with aluminum hydroxide elicit robust and long lasting immune response against SARS-CoV-2. Eur J Pharm Biopharm. 2022:176:43-53. I.F: 5.58 (*Corresponding author )

3. Meena J, Gupta A, Ahuja R, Singh M, Panda AK. Recent advances in Nano-engineered approaches used for enzyme immobilization with enhanced activity. Journal of Molecular Liquids. 2021; 338:116602. I.F: 6.63

4. Meena J, Kumar R, Singh M, Ahmed A, Panda AK. Modulation of immune response and enhanced clearance of Salmonella typhi by delivery of Vi polysaccharide conjugate using PLA nanoparticles. Eur J Pharm Biopharm. 2020;152:270-281. I.F: 5.58

5. Meena J*, Gupta A, Ahuja R, Panda AK, Bhaskar S. Inorganic nanoparticles for natural product delivery: a review. Environmental Chemistry Letters. 2020; 1-12.  I.F: 13.61    (*Corresponding author)

6. Meena J, Ojha R, Muruganandam AV, Krishnamurthy S.Asparagus racemosus competitively inhibits in vitro the acetylcholine and monoamine metabolizing enzymes. Neuroscience letters. 2011;503:6-9. I.F: 3.19

7. Meena J, Goswami DG, Anish CK, Panda AK. Cellular uptake of polylactide particles induces size dependent cytoskeletal remodeling in antigen presenting cells. Biomaterials Science. 2021; 9:7962-7976. IF: 7.59

8. Ahuja R, Shelly A, Meena J, Panda AK. Microparticles entrapping pneumococcal protein SP0845 show improved immunogenicity and temperature stability. Int J Biol Macromol. 2022;203:661-670. I.F: 8.02

9. Singh M, Sori S, Ahuja A, Meena J, Sehgal D, Panda AK. Effect of N-terminal poly histidine-tag on immunogenicity of Streptococcus pnumoniae surface protein SP0845. Int J Biol Macromol. 2020;163:1240-1248. I.F: 8.02

10. Ahuja R, Panwar N, Meena J, Singh M, Sarkar DP, Panda AK.Natural products and polymeric nanocarriers for cancer treatment: A review. Environmental Chemistry Letters. 2020; 43, 67-112. I.F: 13.61

11. Shelly A, Gupta P, Ahuja R, Srichandan S, Meena J, Majumdar T. Impact of Microbiota: A Paradigm for Evolving Herd Immunity against Viral Diseases.Viruses, 2020; 12 (10), 1150. I.F: 5.81

12. Kumar R, Singh M, Meena J, Singhvi P, Thiyagarajan D, Saneja A, Panda A K. Hyaluronic acid - dihydroartemisinin conjugate: Synthesis, characterization and in vitro evaluation in lung cancer cells.Int J Biol Macromol. 2019;133:495-502. I.F: 8.02

13. Oyeyemi O, Adegbeyeni O, Oyeyemi I, Meena J, Panda A. In vitro ovicidal activity of poly lactic acid curcumin-nisin co-entrapped nanoparticle against Fasciola spp. eggs and its reproductive toxicity. Journal of basic and clinical physiology and pharmacology. 2018;29 (1):73-79. I.F: 1.65

14. Anzar N, Mirza MA, Anwer K, Khuroo T, Alshetaili A, Alshahrani SM, Meena J, Hassan Nazia, Telegaonkar S, Panda AK, Iqbal Z. Preparation, evaluation and pharmacokinetic studies of spray dried PLGA polymeric submicron particles of simvastatin for the effective treatment of breast cancer. Journal of Molecular Liquids. 2018;249:609-616 I.F: 6.63

15. Oyeyemi O, Morenikeji O, Afolayan F, Dauda K, Busari Z, MeenaJ and Panda A K. Curcumin- Artesunate Based Polymeric Nanoparticle; Antiplasmodial and Toxicological Evaluation in Murine Mode. Frontiers in Pharmacology. 2018;9:562. I.F: 5.98

16. Busari ZA, Dauda KA, Morenikeji OA, Afolayan F, Oyeyemi OT, Meena J, et al. AntiplasmodialActivity and Toxicological Assessment of Curcumin PLGA-Encapsulated Nanoparticles. Frontiers in Pharmacology. 2017;8:622. I.F: 5.98

17. Dende C, Meena J, Nagarajan P, Nagaraj VA, Panda AK, Padmanaban G. Nanocurcumin is superiorto native curcumin in preventing degenerative changes in Experimental Cerebral Malaria. Scientific reports. 2017;7:10062. I.F: 4.99

18. Dauda K, Busari Z, Morenikeji O, Afolayan F, Oyeyemi O, Meena J, et al. Poly-D, L-lactic-co- glycolicacid-based artesunate nanoparticles; formulation, antimalarial and toxicity assessments. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). 2017;18(11):977-985. I.F: 5.55

19. Panda A, Meena J, Katara R, Majumdar DK. Formulation and characterization of clozapine andrisperidone co-entrapped spray-dried PLGA nanoparticles. Pharmaceutical Development and Technology. 2016;21:43-53. I.F: 3.91

20. Gupta A, Meena J, Sharma D, Gupta P, Gupta UD, Kumar S, et al. Inhalable Particles for "PincerTherapeutics" Targeting Nitazoxanide as Bactericidal and Host-Directed Agent to Macrophages in a Mouse Model of Tuberculosis. Molecular pharmaceutics. 2016;13:3247-55. I.F: 5.36

21. Gupta A, Sharma D, Meena J, Pandya S, Sachan M, Kumar S, et al. Preparation and PreclinicalEvaluation of Inhalable Particles Containing Rapamycin and Anti-Tuberculosis Agents for Induction of Autophagy. Pharmaceutical research. 2016;33:1899-1912. I.F: 4.58

22. Dende C, Meena J, Nagarajan P, Panda AK, Rangarajan PN, Padmanaban G. Simultaneously targetinginflammatory response and parasite sequestration in brain to treat Experimental Cerebral Malaria. Scientific reports. 2015;5:12671. I.F: 4.99

Book Chapters:
1. Meena J*, Gupta A, Ahuja R, Panda AK, Bhaskar S. Inorganic Particles for Delivering Natural Products. Sustainable Agriculture Reviews 44. 2020; 205-241. (*Corresponding author)

2. Ahuja R, Panwar N, Meena J, Sarkar DP, Panda AK. Delivery of Natural Products Using Polymeric Particles for Cancer Chemotherapeutics. Sustainable Agriculture Reviews 43. 2020; 67-112.

1. Meena J and Panda AK. A novel typhoid vaccine comprise of conjugate of Vi polysaccharide with flagellin. Details: Indian patent application 201611002743 filed on 25/01/2016

2. Meena J and Panda AK. A novel conjugate for vaccination against typhoid comparising chemical conjugate of vi polysaccharide and flagellin, a process for producing the same and composition comprising the same. Details: European patent application 17788946.6-111 pct/in2017050142 filed on 21/04/2017 5

3. Meena J and Panda AK. Conjugate for vaccination against typhoid comprising chemical conjugate of Vi polysaccharide and flagellin, a process for producing the same and a composition comprising the conjugate. Details: USA patent application 16096387 published on 09/05/2019

4. Meena J and Panda AK. A highly efficient polymer particulate vaccine formulation entrapping admixture of alum and antigen. Details: Indian patent application 201911036242 filed on 09/09/2019

5. Meena J, Singh M, Srichandan S, Singhvi P, Panda AK. Polymeric nanoparticle based vaccine formulation against SARS CoV-2 and related diseases Details: Indian patent application no 202011035557 filed on 18/08/2020

6. Singh M, Meena J and Panda AK. A Process for promoting germinal centres using polymeric particle based immunization. Details: Indian patent application 202011026508 filed on 23/06/2020

7. Singh M, Meena J, Sori H, Ahuja R, Saxena S, Sehgal D and Panda AK. A novel glycoconjugate vaccine against Streptococcus pneumoniae. Details: Indian patent application no 2020110282033 filed on 02/07/2020