pknayak.phe's picture
Dr. Prasanta Kumar Nayak
Assistant Professor
Department of Pharmaceutical Engineering and Technology IIT BHU
Area of Interest: 

  • BPharm (2004): Biju Patnaik University of Technology, Odisha.
  • MPharm (2006): Department of Pharmaceutics, IT (BHU), Varanasi.
  • PhD (2013): Otago School of Medical Sciences, Dunedin, New Zealand.
  • Teaching: ~10 years
  • Academic Research: ~13 years
  • Industrial Research: ~4 years
  • Primarily Prophylactic Pharmacology and Prophylactic Treatment Strategies 
  • Neuropharmacology and Hippocampal Electrophysiology – Stroke, Memory Impairment, Depression, Chronic Diseases
  • Oncology  –  Pathophysiology of Breast Tumors, Brain Tumors, Gallbladder Tumors, and Colorectal Tumors
  • Undergraduate:
    • BL101-Biology
    • BO202-Human Physiology
    • PH231-General Pharmacology
    • PH432-Neuropharmacotherapeutics
    • UHVII-Universal Human Values-II
    • UHVI-Universal Human Values-I
  • Postgraduate:
    • PH532-Advanced Pharmacology
    • PH534-Clinical Pharmacology​
    • PH535-Advances in Neuropharmacology
    • PH7202-Research Methodology
    • PH504-Applied Pharmacology
  • Neogi K, Murumkar PR, Sharma P, Yadav P, Tewari M, Karunagaran D, Nayak PK, Yadav MR (2022), Design, synthesis and evaluation of 4, 7-disubstituted 8-methoxyquinazoline derivatives as potential cytotoxic agents targeting β-catenin/TCF4 signaling pathway. Translational Oncology 19, 101395.
  • Sharma V,  Firdaus Z, Rai H, Nayak PK, Singh TD, Gautam DNS (2021), Consumption of Ashtanga Ghrita (clarified cow butter added with herb extracts) improves cognitive dysfunction induced by scopolamine in rats via regulation of acetylcholinesterase activity and oxidative stress. Drug Metabolism and Personalized Therapy 36 (4), 337-350.
  • Singh YP, Tej GNVC, Pandey A, Priya K, Pandey P, Shankar G,  Nayak PK, Rai Geeta, Chittiboyina AG, Doerksen RJ, Vishwakarma S, Modi G (2020), Design, synthesis and biological evaluation of novel naturally-inspired multifunctional molecules for the management of Alzheimer’s disease. European Journal of Medicinal Chemistry 198, 112257.
  • Tej GNVC, Neogi K, Nayak PK (2019),Caffeine-enhanced anti-tumor activity of anti-PD1 monoclonal antibody. International Immunopharmacology 77, 106002.
  • Tej GNVC, Neogi K, Verma SS, Gupta SC, Nayak PK (2019), Caffeine-enhanced anti-tumor immune response through decreased expression of PD1 on infiltrated cytotoxic T lymphocytes. European Journal of Pharmacology, 859, 172538.
  • Shivavedi N., Tej GNVC, Neogi K, Nayak PK (2019), Ascorbic acid therapy: A potential strategy against comorbid depression-like behavior in streptozotocin-nicotinamide-induced diabetic rats. Biomedicine & Pharmacotherapy, 109, 351-359.
  • Tej GNVC, Nayak PK (2018), Mechanistic considerations in chemotherapeutic activity of caffeine. Biomedicine and Pharmacotherapy 105: 312-319.
  • Kumar M and Nayak PK (2017), Therapeutic potential of rosmarinic acid in myocardial infarction and post-myocardial infarction depression: the role of tumor necrosis factor-α. The Pharmstudent 28: 18-26.
  • Kumar M and Nayak PK (2017), Psychological sequelae of myocardial infarction. Biomedicine & Pharmacotherapy 95: 487‒496.
  • Shivavedi N, Kumar M, Tej GN, Nayak PK (2017), Metformin and ascorbic acid combination therapy ameliorates type 2 diabetes mellitus and comorbid depression in rats. Brain Research 1674: 1‒9. doi:
  • Kumar M and Nayak PK (2017), Natural phytochemicals: a promising approach in the management of myocardial infarction. Biomedicine & Pharmacotherapy 92: 1138‒1139.
  • Srivastava P, Kumar M, Nayak PK (2016), Role of patient derived cell lines and xenografts in cancer research. The Pharmstudent 27: 40‒48.
  • Sethi KK, Nayak PK, Sarkar H, Verma SM (2016), A rational approach towards the development of human carbonic anhydrase inhibitors as antiepileptic agent. Med Chem (Los Angeles) 6: 405‒410. doi:10.4172/2161-0444.1000377
  • Nayak PK and Kerr DS (2015), Functional preservation of hippocampal CA1 by low-dose GYKI-52466 preconditioning in a rat model of hypoxic-ischemic brain injury. Brain Research 1613: 100‒109.
  • Nayak PK, Kerr DS (2013), Low-dose GYKI-52466: Prophylactic preconditioning confers long-term neuroprotection and functional recovery following hypoxic‒ischaemic brain injury. Neuroscience 232: 128‒138.
  • Nayak PK, Zhang H and Kerr DS (2013), Determination of 1-(4′-aminophenyl)-4-methyl-7,8-methylene-dioxy-2,3-benzodiazepine by high-performance liquid chromatography–diode array detection in plasma and brain in healthy and hypoxic–ischaemic rats. Neuroscience 232: 139‒150.
  • Mandhane S, Nayak PK, Soni D, Jain S, Ashton J, Rajamannar T (2012), Induction of glucose intolerance by acute administration of rimonabant. Pharmacology 89(5‒6): 339‒347.
  • Bhattamishra SK, Nayak PK, Singh PN, Singh SK (2006), Anti-inflammatory and analgesic activities of Marsilea minuta Linn. Drug Lines 9 (1&2): 42‒45.

PhD Students:
1. Mr Gullanki Naga Venkata Charan Tej, M.Pharm.
2. Mr Kaushik Neogi, M.Pharm.
3. Mr Himanshu Verma, ​M.Pharm.​
4. Mr K Venkateswarlu, M.Pharm.

M.Pharm./M.Tech. Students:
1. Mr Neeraj Bobde, B.Pharm.
2. Mr Nagare Santosh G, B.Pharm.
3. Mr Rahul Baghel, B.Pharm.
4. Mr Korra Ramesh Naik, B.Pharm.