skshrivastava.phe's picture
Prof. Sushant Kumar Shrivastava
Professor
Department of Pharmaceutical Engineering and Technology
skshrivastava.phe@iitbhu.ac.in
91-542-6702725
91-9452156527
Area of Interest: 
Pharmaceutical Medicinal and Computational chemistry

  • B Pharm.: Dr. H S Gaur Vishwavidhyalaya, Sagar, MP
  • M Pharm.: Dr. H S Gaur Vishwavidhyalaya, Sagar, MP
  • PhD.: Devi Ahilya Vishwavidhyalaya, Indore, MP
  • Teaching: 27 years
  • Undergraduate:
    • Pharmaceutical Organic Chemistry II
    • Pharmaceutical Analysis
    • Pharmaceutical Biochemistry
    • Pharmaceutical Medicinal Chemistry I, II & III
    • Drug Design 
  • Postgraduate:
    • Chemistry of Synthetic Drugs
    • Drug Design
    • Advanced Medicinal Chemistry
  • PhD:
    • Advanced Pharmaceutical Chemistry
  • Rational Drug Design and Molecular Modeling
  • Synthetic Medicinal Chemistry
  • Inflammation, Alzheimer's disease, and cancer
  • UGC Research Project 37-52/2009(SR) “Synthesis and evaluation of Lamotrigine-Glutathione inducing amino acid conjugates to minimise hepatotoxicity: A Prodrug Approach” (11.0 lakhs)
  • IIT (BHU) sponsored research project entitled 25/03/2014 “Design, Synthesis and Evaluation of Some New Heterocyclic Compounds as Potential Hypoglycemic and Antimicrobial Agents” (15.0 Lakhs).
  • IIT (BHU) sponsored research project entitled 04/01/2016 “Design, synthesis, molecular modeling and evaluation of some novel heterocyclic compounds as potential anti-hypoglycemic agents”(Rs 13,20,374/-). 
  • IIT(BHU) Post Doctoral Fellowship- Ref. IIT (BHU)/ R&D/PDF/2015-16/4085/L dated 20-02-2016.
  • Mentor of Young Scientist- Mr. Piyoosh Sharma for the research funded project from Department of Health Research (DHR), Ministry of Health and Family Welfare, Govt. of India; HRD Fellowship – (Rs 45,12,000/-) for 3 years (2016-2019).
  • SERB-CRG sponsored research project entitled "Design and Development of potential multifunctional molecular hybrids for the treatment of Alzheimer’s disease"- (Rs. 28,28,600/-) for 3 years dated- Janurary 2022
  • ICMR-DHR sponsored reserch project entitled " Design and Development of Molecular Hybrids on a Multifunctional Framework for Regulating Cholinesterases, β-secretase 1, Amyloid-β, and Oxidative Stress Against Alzheimer’s Disease"- (Rs. 41,80,895/-) for 3 years dated- December,2020

Total Publications: 104
Citations:
Citations: > 2062;                       h-index: 25;                 i-10 index: 58
(Source: Google Scholar https://scholar.google.co.in/citations?hl=en&user=o6lTDWIAAAAJ)

S. No. Author(s) Title Name of Journal Vol. Page Year I.F.
1. Poorvi Saraf, Prabhash Nath Tripathi, Manish Kumar Tripathi, Avanish Tripathi, Himanshu Verma, Digambar Kumar Waiker, Royana Singh, Sushant Kumar Shrivastava Novel 5, 6-diphenyl-1, 2, 4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity Bioorganic Chemistry 129 106147 2022 5.3
2. Sushant Kumar Shrivastava, Ojaswi Sinha, Munish Kumar, Digambar Kumar Waiker, Akash Verma, Prabhash Nath Tripathi, Bhagwati Bhardwaj, Poorvi Saraf Synthesis, characterization, and biological evaluation of some novel ϒ-aminobutyric acid aminotransferase (GABA-AT) inhibitors Medicinal Chemistry Research 31 1594-1610 2022 2.351
3. Urmilesh Singh, Laxmi, Prabhakar Singh, Ankit Kumar Singh, Sweksha Singh, Deepak Kumar, Sushant Kumar Shrivastava, Ravi Kumar Asthana In silico and in vitro evaluation of extract derived from Dunaliella salina, a halotolerant microalga for its antifungal and antibacterial activity Journal of Biomolecular Structure and Dynamics 40 1-15 2022 3.392
4. Sushant K Shrivastava, Avhad Ashok Nivrutti, Bhagwati Bhardwaj, Digambar Kumar Waiker, Akash Verma, Prabhash Nath Tripathi, Manish Tripathi, Poorvi Saraf Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease Journal of Molecular Structure 1262 132979 2022 3.841
5. Wei Yu, Yiming Ma, Sushant K Shrivastava, Rakesh K Srivastava, Sharmila Shankar Chronic alcohol exposure induces hepatocyte damage by inducing oxidative stress, SATB2 and stem cell‐like characteristics, and activating lipogenesis Journal of Cellular and Molecular Medicine 26 2119-2131 2022 5.295
6. Akash Verma, Digambar Kumar Waiker, Bhagwati Bhardwaj, Poorvi Saraf, Sushant K Shrivastava The molecular mechanism, targets, and novel molecules in the treatment of Alzheimer’s disease Bioorganic Chemistry 119 105562 2022 5.30
7. Salunke Prashant Ramrao, Akash Verma, Digambar Kumar Waiker, Prabhash Nath Tripathi, Sushant Kumar Shrivastava Design, synthesis, and evaluation of some novel biphenyl imidazole derivatives for the treatment of Alzheimer's disease Journal of Molecular Structure 1246 131152 2021 3.841
8. Kamta P Namdeo, Sushant K Shrivastava, Ramesh Chandra Synthesis of Some Glycine Nicotinates and in-vivo Evaluation of Anti-Convulsant Activity for their Brain specific Slow Release Action INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH 55 888-893 2021 0.5
9. Choube, P.K.,Tripathi, A.,Tripathi,M.K.,Seth,A.,Shrivastava,S.K Design,synthesis and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatmentof Alzhiemer’s Disese Bioorganic Chemistry 111 104922 2021 4.8
10.. Singh,U,Singh,P.,Singh,A.K., Laxmi, Kumar,D, Tilak,R.,Shrivastava,S.K. and Asthana,R. Identification of antifungal and antibacterial biomolecules from a cyanobacterium, Artrospira platensis Algal Research 54 102215 2021 5.0
11. Choubey,P.K., Tripathi,A., Sharma,P. and Shrivastava,S.K Design,synthesis and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer’s disease Bioorganic and Medicinal Chemistry 28 (22) 115721 2020 3.0
12. Chikhale,R.V.,Gurav,S.S.,Patil,R.B., Sinha,S.K., Prasad,S.K., Shakya,A.,Shrivastava,S.K.,Gurav,N.S., Prasad,R.S. Sars-cov-2 host entry and replication inhibitors from Indian ginseng: an in-silico approach Journal of Biomolecular Structure and Dynamics   1-4 2020 4.98
13. Lam,B.Q., Shrivastava,S.K., Shrivastava,A., Shankar,S., Srivastava,R. The impact of obesity and diabetes mellitus on pancreatic cancer:Molecular mechanism and clinical perspectives Journal of Cellular and Molecular Medicine 24 (14) 7706-7716 2020 4.6
14. Tripathi,M.K., Sharma,P., Tripathi,A., Tripathi,P.N., Srivastava,P.,Seth,A.  Shrivastava,S.K. Computational exploration and experimental validation to identify a dual inhibitor of cholinesterase and amyloid-beta for the treatment of Alzheimer’s disease Journal of Computer Aided Molecular Design 34 983-1002 2020 2.54
15. Tripathi, A., Choubey, P.K., Sharma, P., Seth, A., Saraf, P., Shrivastava, S.K. Design, Synthesis, and Biological Evaluation of Ferulic Acid Based 1,3,4-Oxadiazole Hybrids as Multifunctional Therapeutics for the Treatment of Alzheimer’s Disease Bioorganic Chemistry 95 103506 2020 4.8
16. Tripathi, A., Choubey, P.K., Sharma, P., Seth, A., Tripathi, M.K., Shrivastava, S.K. Design and Development of Multifunctional Hybrids of Ferulic Acid and 1,3,4-Oxadiazoles for the Treatment of Alzheimer’s Disease Current Trends in Biotechnology  and Pharmacy 14 (1) 81-96 2020 -
17. Tripathi, A., Choubey, P.K., Sharma, P., Seth, A., Tripathi, P.N., Tripathi, M.K., Prajapati, S.K., Krishnamurthy, S., Shrivastava, S.K. Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease European Journal of Medicinal Chemistry 183 111707 2019 5.57
18. Sharma, P., Tripathi, A., Tripathi, P.N., Singh, S.S., Singh, S.P., Shrivastava, S.K. Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer’s Disease ACS Chemical Neuroscience 10 4361-4384 2019 4.48
19. Srivastava, P., Tripathi, P.N., Sharma, P., Shrivastava, S.K. Design, synthesis, and evaluation of novel N-(4-phenoxybenzyl)aniline derivatives targeting acetylcholinesterase, β-amyloid aggregation and oxidative stress to treat Alzheimer’s disease Bioorganic & Medicinal Chemistry 27 (16) 3650-3662 2019 3.0
20. Mishra, P., Sharma, P., Tripathi, P.N., Gupta, S.K., Srivastava, P., Seth, A., Tripathi, A., Krishnamurthy, S., Shrivastava, S.K. Design and Development of 1,3,4-Oxadiazole Derivatives as Potential Inhibitors of Acetylcholinesterase to Ameliorate Scopolamine-Induced Cognitive Dysfunctions Bioorganic Chemistry 85 103025 2019 4.8
21. Tripathi, P.N., Srivastava, P, Sharma, P., Seth, A., Shrivastava, S.K. Design and development of novel N-(pyrimidin-2-yl)-1, 3, 4-oxadiazole hybrids to treat cognitive dysfunctions Bioorganic & Medicinal Chemistry 27 (7) 1327-1340 2019 3.0
22. Sharma, P., Srivastava, P., Seth, A., Tripathi, P.N., Banerjee, A.G., Shrivastava, S.K. Comprehensive review of mechanisms of pathogenesis involved in Alzheimer’s disease and potential therapeutic strategies Progress in Neurobiology 174 53-89 2019 14.16
23. Fu, J., Shrivastava, A., Shrivastava, S.K., Srivastava, R.K., Shankar, S. Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent International Journal of Oncology 54 (4) 1306-1316 2019 3.33
24. Sharma, P., Tripathi, A., Tripathi, P.N., Prajapati, S.K., Seth, A., Tripathi, M.K., Srivastava, P., Tiwari, V., Krishnamurthy, S., Shrivastava, S.K. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer’s disease European Journal of Medicinal Chemistry 167 510-524 2019 5.57
25. Tripathi, P.N., Srivastava, P., Sharma, P., Tripathi, M.K., Seth, A., Tripathi, A., Rai, S.N., Singh, S.P. Shrivastava, S.K. Biphenyl-3-oxo-1, 2, 4-triazine linked piperazine derivatives as potential cholinesterase inhibitors with anti-oxidant property to improve the learning and memory Bioorganic Chemistry 85 82-96 2019 4.8
26. Srivastava, P., Tripathi, P.N., Sharma, P., Rai, S.N., Singh, S.P., Srivastava, R.K., Shankar, S., Shrivastava, S.K. Design and development of some phenyl benzoxazole derivatives as a potent acetylcholinesterase inhibitor with antioxidant property to enhance learning and memory European Journal of Medicinal Chemistry 163 116-135 2019 5.57
27. Besan, M., Gautam, M.K., Shrivastava, S.K. Development of 1, 4-Naphthoquinones as Potential Epidermal Growth Factor Receptor Inhibitors For The Treatment of Cancer Current Trends in Biotechnology and Pharmacy 13 (3) 283-308 2019 -
28. Besan, M., Gautam, M.K., Shrivastava, S.K. Design, Synthesis, Cytotoxicity Evaluation, and Molecular Docking Studies of 1,3,4- Oxadiazole substituted 1,4-Naphthoquinone Derivatives Current Trends in Biotechnology and Pharmacy 13 (3) 243-258 2019 -
29. Srivastava, P., Tripathi, P.N., Sharma, P.,  Shrivastava, S.K. Quantitive Structre Activity Relationship based Design, Synthesis, and Evaluation of Novel Diarylether derivatives as a potent Acetylcholinesterase inhibitor and Antioxidant to treat Cognitive dysfunctions Current Trends in Biotechnology and Pharmacy 13 (2) 124-145 2019 -
30. Shrivastava, S.K. et al. Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer’s disease Bioorganic Chemistry 82 211-223 2019 4.8
31. Singh, N.K., Garabadu, D., Sharma, P., Shrivastava, S.K. & Mishra, P. Anti-allergy and anti-tussive activity of Clitoria ternatea L. in experimental animals. Journal of Ethnopharmacology 224 15-26 2018 2.98
32. Shrivastava, S.K., Tripathi, P., Srivastava, P., Sharma, P., Tripathi, A., Seth, A., Tripathi, M.K. Synthesis, evaluation and docking studies of some 4-thiazolone derivatives as effective lipoxygenase inhibitors. Chemical Papers 72 (11) 2769-2783 2018 1.25
33. Seth, A., Sharma, P., Tripathi, A., Choubey, P., Srivastava, P., Tripathi, P. & Shrivastava, S.K. Design, Synthesis, Evaluation and Computational Studies of Nipecotic Acid-Acetonaphthone Hybrids as Potential Antiepileptic Agents. Medicinal Chemistry 14 (4) 409-426 2018 2.33
34. Seth, A., Sharma, P.A., Tripathi, A., Choubey, P.K., Srivastava, P., Tripathi, P.N. & Shrivastava, S.K. Design, synthesis, evaluation and molecular modeling studies of some novel N-substituted piperidine-3-carboxylic acid derivatives as potential anticonvulsants. Medicinal Chemistry Research 27 1206-1225 2018 1.27
35. Shrivastava, S.K., Srivastava, P., Bandresh, R., Tripathi, P.N. & Tripathi, A. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity. Bioorganic & Medicinal Chemistry 25 4424-4432 2017 3.0
36. Kulshrestha, A., Das, N., Banerjee, A.G. & Shrivastava, S.K. Design, synthesis and pharmacological evaluation of some pyrazolopyrimidin-6 (7H)-ones and tricyclic 8-oxo-dihydrooxazolopyrazolopyrimidin-9-ium chloride derivatives. Arabian Journal of Chemistry 10 S3614-S3621 2017
 		 4.76
37. Shrivastava, S.K., Srivastava, P., Upendra, T., Tripathi, P.N. & Sinha, S.K. Design, synthesis and evaluation of some N-methylenebenzenamine derivatives as selective acetylcholinesterase (AChE) inhibitor and antioxidant to enhance learning and memory. Bioorganic & Medicinal Chemistry 25 1471-1480 2017 3.0
38. Banerjee, A.G., Das, N., Shengule, S.A., Sharma, P.A., Srivastava, R.S. & Shrivastava, S.K. Design, synthesis, evaluation and molecular modelling studies of some novel 5, 6-diphenyl-1, 2, 4-triazin-3 (2H)-ones bearing five-member heterocyclic moieties as potential COX-2 inhibitors: A hybrid pharmacophore approach. Bioorganic Chemistry 69 102-120 2016 4.8
39. Shrivastava, S.K., Batham, A., Sinha, S.K., Parida, T.K., Garabadu, D. & Choubey, P.K. Design, synthesis and evaluation of novel thiazolidinedione derivatives as anti-hyperglycemic and anti-hyperlipidemic agents. Medicinal Chemistry Research 25 2258-2266 2016 1.27
40. Banerjee, A.G., Kothapalli, L.P., Sharma, P.A., Thomas, A.B., Nanda, R.K., Shrivastava, S.K. & Khatanglekar, V.V. A facile microwave assisted one pot synthesis of novel xanthene derivatives as potential anti-inflammatory and analgesic agents. Arabian Journal of Chemistry 9 S480-S489 2016 4.76
41. Shah, K., Chabbraa, S., Agrawala, N., Upadhyaya, P.K., Shrivastavab, S.K., Upmanyuc, N. & Mishraa, P. Synthesis and biological evaluation of substituted benzimidazoles. J. Indian Chemical Society 93 1009-1018 2016 0.11
42. Pandit, N., Shah, K., Agrawal, N., Upmanyu, N., Shrivastava, S.K. & Mishra, P. Synthesis, characterization and biological evaluation of some novel fluoroquinolones. Medicinal Chemistry Research
 		 25 843-851 2016 1.27
43. Banerjee, A.G., Das, N., Shengule, S.A., Srivastava, R.S. & Shrivastava, S.K. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6–diphenyl–1, 2, 4–triazin–3 (2H)–one derivatives bearing 5–substituted 1, 3, 4–oxadiazole as potential anti–inflammatory and analgesic agents. European Journal of Medicinal Chemistry 101 81-95 2015 5.57
44. Shah, K., Shrivastava, S.K. & Mishra, P. Formulation and evaluation of suspensions: Mefenamic acid prodrugs. Pakistan Journal Pharmaceutical Sciences 27 - 2014 0.64
45. Shah, K., Shrivastava, S.K. & Mishra, P. Synthesis, Kinetics and Pharmacological Comparison of a Mutual Prodrug of Mefenamic Acid to Related Physical Mixture. Pharmaceutical Chemistry Journal 48 253-259 2014 0.44
46. Das, N., G Banerjee, A. & K Shrivastava, S. Design Synthesis and Pharmacological Evaluation of N3 Aryl/Heteroaryl Substituted 2-((Benzyloxy and Phenylthio) Methyl) 6, 7-dimethoxyquinazolin-4 (3H)-ones as anticonvulsants. Medicinal Chemistry 10 800-809 2014 2.33
47. Das, N., Garabadu, D., Banerjee, A.G., Krishnamurthy, S. & Shrivastava, S.K. Synthesis and pharmacological evaluation of some N3-aryl/heteroaryl-substituted 2-(2-chlorostyryl)-6, 7-dimethoxy-quinazolin-4 (3H)-ones as potential anticonvulsant agents. Medicinal Chemistry Research 23 4167-4176 2014 1.27
48. Sreelakshmi, V., Uma Maheshwari Rao, V., Pugazhendhy, S., Shrivastava, S. & Sunitha, M. Development and validation of simvastatin by RP-HPLC method in bulk drug and pharmaceutical dosage forms. American Journal of Pharmaceutical Technology & Research 3 (5) - 2013 0.98
49. Sinha, S.K. & Shrivastava, S.K. Design, synthesis and evaluation of some new 4-aminopyridine derivatives in learning and memory. Bioorganic & Medicinal Chemistry Letters
 		 23 2984-2989 2013 2.45
50. Shukla, S., Srivastava, R.S., Shrivastava, S.K., Sodhi, A. & Kumar, P.. Synthesis, cytotoxic evaluation, docking and in silico predictions of 4-arylideneamino/cycloalkylidineamino 1, 2-naphthoquinone thiosemicarbazones Journal of Enzyme Inhibition and Medicinal Chemistry 28 1192-1198 2013 4.29
51. Shah, K., Chhabra, S., Shrivastava, S.K. & Mishra, P. Benzimidazole: a promising pharmacophore. Medicinal Chemistry Research 22 5077-5104 2013 1.27
52. Sinha, S.K. & Shrivastava, S.K. Synthesis, evaluation and molecular dynamics study of some new 4-aminopyridine semicarbazones as an antiamnesic and cognition enhancing agents. Bioorganic & Medicinal Chemistry 21
 		 5451-5460 2013 3.0
53. Sreelakshmi, V., Rao, V.U.M., Pugazhendhy, S. & Shrivastava, S.K. Study of forced degradation behavior of simvastatin by rp–hplc and development of a validated stability indicating assay method. Inventi Rapid: Pharm Analysis & Quality Assurance - - 2013 -
54. Shrivastava, P., Shrivastava, A., Sinha, S. & Shrivastava, S.K. Dextran carrier macromolecules for colon-specific delivery of 5-aminosalicylic acid Indian Journal of Pharmaceutical Sciences 75 277 2013 0.66
55. Shukla, S., Srivastava, R., Shrivastava, S., Sodhi, A. & Kumar, P. Synthesis, characterization, in vitro anticancer activity, and docking of Schiff bases of 4-amino-1, 2-naphthoquinone. Medicinal Chemistry Research 22 1604-1617 2013 1.27
56. Shah, K., Shrivastava, S.K. & Mishra, P. Evaluation of mefenamic acid mutual prodrugs. Medicinal Chemistry Research 22 70-77 2013 1.27
57. Das, N., Dash, B., Dhanawat, M. & Shrivastava, S. Design, synthesis, preliminary pharmacological evaluation, and docking studies of pyrazoline derivatives. Chemical Papers
 		 66 67-74 2012 1.25
58. Sinha, S.K., Praveen, B., Shrivastava, P.K. & Shrivastava, S.K. Synthesis, characterization and biological evaluation of some glutathione inducing amino acid conjugates of valproic acid with reduced hepatotoxicity. Asian Pacific Journal of Tropical Disease 2
 		 S218-S222 2012 1.13
59 Shah, K., Shrivastava, S.K. & Mishra, P. Synthesis, kinetics and pharmacological evaluation of mefenamic acid mutual prodrug. Acta Poloniae Pharmaceutica 70 905-977 2012 0.74
60. Sinha, S.K. & Shrivastava, S.K. Synthesis and evaluation of some new 4-aminopyridine derivatives as a potent antiamnesic and cognition enhancing drugs. Medicinal Chemistry Research 21 4395-4402 2012 1.27
61. Dhanawat, M., Banerjee, A.G. & Shrivastava, S. K. Design, synthesis, and anticonvulsant screening of some substituted piperazine and aniline derivatives of 5-phenyl-oxazolidin-2, 4-diones and 5, 5-diphenylimidazolidin-2, 4 diones. Medicinal Chemistry Research 21 2807-2822 2012 1.27
62. Kulshrestha, A., Dhanawat, M., Das, N. & K Shrivastava, S. Small Molecules Antileishmanials: A Review. Letters in Drug Design & Discovery 9 535-548 2012 1.17
63. Shukla, S., Kumar, P., Das, N., Hari Narayana Moorthy, N., Shrivastava, S., Trivedi, P. & Shyam Srivastava, R. Synthesis, characterization, biological evaluation and docking of coumarin coupled thiazolidinedione derivatives and its bioisosteres as PPARγ agonists. Medicinal Chemistry 8 834-845 2012 2.33
64. Das, N., Dhanawat, M. & Shrivastava, S.K. An overview on antiepileptic drugs. Drug Discoveries & Therapeutics 6 178-193 2012 1.47
65. Shukla, S., Srivastava, R., Shrivastava, S., Sodhi, A. & Kumar, P. Synthesis, characterization and antiproliferative activity of 1, 2-naphthoquinone and its derivatives. Applied Biochemistry and Biotechnology 167 1430-1445 2012 1.75
66. Namdeo, K.P., Shrivastava, S.K. & Chandra, R. Synthesis and In-vivo Anti-convulsant Activity of Prodrug of 3-Alkylglutamic Acid in Albino Rats. Indian Journal of Pharmaceutical Educationand Research 46 179-184 2012 0.25
67. Shukla, S., Srivastava, R.S., Shrivastava, S.K., Sodhi, A. & Kumar, P. Synthesis, molecular docking and biological evaluation of 4-cycloalkylidineamino 1,2-naphthoquinone semicarbazones as anticancer agents. Asian Pacific Journal of Tropical Biomedicine 2
 		 S1040-S1046 2012 1.70
68. Sinha, S.K., Shrivastava, P.K. & Shrivastava, S.K. Development and validation of a HPLC method for the simultaneous estimation of amlodipin and telmisartan in pharmaceutical dosage form. Asian Pacific Journal of Tropical Biomedicine 2
 		 S312-S315 2012 1.70
69. Shukla, S., Kumar , P., Moorthy, N., Shrivastava, S., Trivedi, P. & Srivastava, R. QSAR Studies on trans-3, 4’-bispyridinylethylenes as a potent and novel inhibitor of Protein Kinase b (PKB) having inhibitory action against myeloma cells. International Journal of Pure and Applied Chemistry 6 79-87 2011 -
70. Dhanawat, M., Das, N. & Shrivastava, S.K. Design, synthesis, anticonvulsant screening and 5HT1A/2A receptor affinity of N (3)-substituted 2, 4-imidazolidinediones and oxazolidinediones. Drug Discoveries &Therapeutics
 		 5 227-237 2011 1.47
71. Sinha, S.K., Shrivastava, P.K. & Shrivastava, S.K. Synthesis, characterisation, and biological activity of three new amide prodrugs of lamotrigine with reduced hepatotoxicity. Chemical Papers 65 70-76 2011 1.25
72. Namdeo, K. & Shrivastava, S.K. Synthesis and Anticonvulsant Activity of Prodrug of Gabapentin. Asian Journal of Chemistry 23 1861 2011 0.14
73. Pugazhendhy, S., Shrivastava, P.K., Sinha, S.K. & Shrivastava, S.K. Lamotrigine–dextran conjugates-synthesis, characterization, and biological evaluation. Medicinal Chemistry Research 20
 		 595-600 2011 1.27
74. Das, N., Dhanawat, M., Kulshrestha, A. & K Shrivastava, S. K. Pharmacophoric modeling and atom-based 3D-QSAR of novel 1-Aryl-3-(1-acylpiperidin-4-yl) urea as human soluble epoxide hydrolase inhibitors (sEHIs). Medicinal Chemistry 7 581-592 2011 2.33
75. Shrivastava, P.K., Singh, R. & Shrivastava, S.K. Dextran successful carrier molecule for the delivery of NSAIDs with reduced gastrointestinal effect. Journal of Drug Delivery Science and Technology 20 135 2010 1.19
76. Das, N., Dhanawat, M., Dash, B., Nagarwal, R. & Shrivastava, S. Codrug: an efficient approach for drug optimization. European Journal of Pharmaceutical Sciences 41 571-588 2010 3.75
77. Shrivastava, P., Singh, R. & Shrivastava, S. K. Polyamidoamine dendrimer and dextran conjugates: preparation, characterization, and in vitro and in vivo evaluation. Chemical Papers 64 592-601 2010 1.25
78. Verma, A., Das, N., Dhanawat, M. & Shrivastava, S.K. Conjugation of some NSAIDs with 5-phenyl-2-aminothiazole for reduced ulcerogenicity. Thai J Pharm Sci 34 49-57 2010 0.13
79. Shukla, S., Kumar, P., Srivastava, R. & Trivedi, P. RP-HPLC method development and its validation for simultaneous estimation of Alprazolam and Fluoxetine hydrochloride in pharmaceutical dosage form. Eurasian Journal of Analytical Chemistry 5 239-245 2010 -
80. Namdeo, K., Shekhar, V., Bodakhe, S., Shrivastava, S.K. & Dangi, J. Chemical investigations of honey: a multiactive component of herbal therapeutic agent. International Journal of Research in Ayurveda and Pharmacy (IJRAP) 1 85-89 2010 0.36
81. Shrivastava, P. &  Shrivastava, S. K. Dextran carrier macromolecule for colon specific delivery of celecoxib. Current drug Delivery 7 144-151 2010 2.51
82. Dhanawat, M. & Shrivastava, S.K. Solid-phase synthesis of oligosaccharide drugs: a review. Mini Reviews in Medicinal Chemistry 9 169-185 2009 2.66
83. Dhanawat, M., Das, N., Nagarwal, R.C. & Shrivastava, S. K. Antimalarial drug development: past to present scenario. Mini Reviews in Medicinal Chemistry 9
 		 1447-1469 2009 2.66
84. Shrivastava, P.K., Basniwal, P.K., Shrivastava, S.K. & Jain, D. Validated RP-HPLC method for estimation of ezetimibe in different tablet dosage form. Int. J. Ph. Sci 1 174-181 2009 -
85. Shrivastava, P.K. & Shrivastava, S.K. Stress stability studies and the estimation of lamotrigine in pharmaceutical formulation by validated RP-HPLC method. Indian Journal of Pharm. Education & Research 43 156-161 2009 0.25
86. Shrivastava, P. & Shrivastava, S. Dextran polysaccharides: successful macromolecular carrier for drug delivery. Int J Pharm Sci 1 353-368 2009 -
87. Praveen, B., Shrivastava, P. & Shrivastava, S.K. In-Vitro release and pharmacological study of synthesized valproic acid-dextran conjugate. Acta Pharmaceutica Sciencia 51 169-176 2009 0.14
88. Shrivastava, P., Basniwal, P., Jain, D. & Shrivastava, S. Concurrent estimation of clopidogrel bisulfate and aspirin in tablets by validated RP-HPLC method. Indian Journal of Pharmaceutical Sciences 70 667 2008 0.66
89. Das, N., Verma, A., Shrivastava, P.K. & Shrivastava, S.K. Synthesis and biological evaluation of some new aryl pyrazol-3-one derivatives as potential hypoglycemic agents. Indian Journal of Chemistry-B 47B 1555-1558 2008 0.35
90. Shrivastava, S.K., Jain, D., Shrivastava, P.K. & Trivedi, P. Flurbiprofen and Suprofen Conjugates: Synthesis, Characterization and Biological Evaluation. Tropical Journal of Pharmaceutical Research 8 221-229 2008 0.56
91. Shrivastava, S.K., Shrivastava, P.K. & Praveen, B. Synthesis, Characterization, and Biological Evaluation of Some New Derivatives of Valproic acid and Gabapentin: A Prodrug Approach. Journal of Pharmacy and Pharmacology I A-19 2008 2.40
92. Shrivastava, P.K., Basniwal, P.K. & Jain, D. Alkaline Hydrolysis of Pioglitazone Hydrochloride by RP-LC: Stress Stability Study. Acta Pharmaceutica Sciencia 50 41-46 2008 0.14
93. Shrivastava, P., Basniwal, P., Saxena, V., Jain, D. & Shrivatava, S.K. Simultaneous estimation of atorvastatin calcium and aspirin in capsule dosage form by validated RP-HPLC method. Journal of Pharmaceutical Research 6 126-128 2007 1.35
94. Namdeo, K., Shrivastava, S. & Chandra, R. Synthesis and antiparkinson activity of mutual prodrug and chemical delivery system Journal of the Institution Chemist (India) 79 97-110 2007 -
95. Namdeo, K.P., Bodakhe, S., &Shrivastava, S. Phytochemical and biological investigation on calotropis procera. Journal of Science and Pharmacy 8 137-140 2007 -
96. Karthikeyan, C., Kumar, P.M., Moorthy, N., Shrivastava, S. & Trivedi, P. Quantitative structure activity relationships of some selective inhibitors of glucagon receptor: A hansch approach. Asian J. Biochem 1 307-315 2006 1.17
97. Jaiswal, D., Karthikeyan, C., Shrivastava, S.K. & Trivedi, P. QSAR modeling of sulfonamide inhibitors of histone deacetylase. Internet Electron. J. Mol. Des 5 345-354 2006 0.5
98. Shrivastava, P., Basniwal, P.K., Jain, D. & Shrivastava, S.K. RP- HPLC Method for estimation of pioglitazone hydrochloride in tablet formulation Asian Journal of Pharmaceutics 1 55-59 2006 0.46
99. Shrivastava, S., Jain, D. & Trivedi, P. Dextrans—potential polymeric drug carriers for suprofen. Die Pharmazie 58
 		 804-806 2003 1.13
100. Shrivastava, S., Jain, D. & Trivedi, P. Dextrans–potential polymeric drug carriers for flurbiprofen. Die Pharmazie 58 389-391 2003 1.13
101. Shrivastava, S.K., Singh, G. & Basniwal, P.K. Boswillic acid: an alternative anti-inflammatory therapy. Indian Journal of Natural Products 19 14-20 2003 -
102. Mathur, P., Parashar, K., Shrivastava S. & Shrivastava, S.K. Synthesis of a novel metal chelating ion exchange resin specific for zinc Indian Journal of Chemistry- Section A 39A 1327-1330 2000 0.49
103. Shrivastava, S.K., & Bhandari, A. Review Article: Managment of Schizophrenia. Indian Drugs 34 617-624 1997 0.14
104. Shrivastava, S., Uppadhyay, R., Trivedi, P. & Jain, D. Synthesis and Evaluation of Amino Acid Analogues of Valproic Acid. Indian Drugs 33 571-573 1996 0.14

 

S. No. Patent Title Name of Applicant Patent No. Award Date Agency/ Country Status
1. A Process for Preparation of Pharmaceutical Active Novel N-(9-(4- chlorophenyl)-3- hydroxy-9H- xanthene-7-yl)- acetamide. Modgalya, D., Banerjee, A.G., Sharma, P., Shrivastava, S.K., Bhattacharjee, J. and Singh, S. 3858/DEL/2011 Published- 02.06.2017 India Published
2. Choline Esterase Inhibiting Compounds, Compositions and Process Thereof Shrivastava, S.K., & Sinha, S. 201611011127 Published- 26.01.2018 India Published
3. Compositions and methods for reducing cell viability Shrivastava. S.K., Srivsatava, R.K., Shankar, S., Tripathi, P.N., Srivastava, P. 2932719-019-US1 Filed- 30.04.2018 United States Filed
4. Methods for treating cancer and metabolic syndrome Shrivastava. S.K., Srivsatava, R.K., Shankar, S.,Tripathi, P.N., Srivastava, P., Sharma P. 2932719-025-US1 Filed- 04.05.2018 United States Filed
5. 5-Oxoisoxazolidine– 2–carboxamide compounds as inhibitors of cyclo- oxygenase and lipo- oxygenase as anti- inflammatory analgesic agents Shrivastava, S.K., Yadav, S., Tripathi, P.N. & Srivastava, P. 201811019910 Filed- 28.05.2018 India Filed
6. Composition and methods for treating cancer Shrivastava, S.K., Shrivastava, R., Shrivastava, S, Tripathi, P.N. & Srivastava, P. 62/728439-2932719-053-US1 Filed- 07.09.2018 United States Filed
7. Synthesis of N-benzylpiperidine and 5-(2,4-dichlorophenyl)-1,3,4-oxadiazole hybrid with multifunctional activities against Alzheimer’s Disease Sharma, P., Tripathi, A., Tripathi P.N., Avhad, A., Shrivastava, S.K. 201911034164 Filed- 24.08.2019 India Filed
8. A novel compound for treating Alzheimer's disease and a method of preparation thereof Tripathi, A., Sharma, P., Choubey, P.K., Shrivastava, S.K. 201911034300 Filed- 26.08.2019 India Filed
9. N-(1-benzylpiperidin-4-yl)-5-(4-(trifluoromethyl)
phenyl)-1,3,4-oxadiazol-2-amine as multitargeted
ligand to treat Alzheimer’s disease		 Sharma, P., Tripathi, A., Tripathi P.N., Salunke, P., Shrivastava, S.K. 201911034930 Filed- 29.08.2019 India Filed
10. Synthesis of 2-(4-bromophenyl)-5-(4-(pyridin-2-yl)Piperazin-1-yl)-1,3,4-oxadiazole for treating Alzheimer's disease and method of preparation thereof Tripathi, A., Sharma, P., Choubey, P.K., Shrivastava, S.K. 201911034931 Filed- 29.08.2019 India Filed
11. Composition and Methods for treating cancer Prabhash Nath Tripathi and Pavan Srivastava Rakesh srivastava,Sharmila Shankar, Sushant Kumar Shrivastava US 11,286,241 B2 Published- 29.03.2022 United States Published
12. Compositions and methods for treating cancer Rakesh K Srivastava, Sharmila Shankar, Sushant Kumar Shrivastava, Prabhash Nath Tripathi, Pavan Srivastava 11286241 Published- 29.03.2022 United States Published
  • Tripathi MK, Shrivastava SK, Karthikeyan S, Sinha D, Nath A. Application of Machine Learning and Molecular Modeling in Drug Discovery and Cheminformatics. InAdvanced AI Techniques and Applications in Bioinformatics 2021 Oct 17 (pp. 201-214). CRC Press.
  • Sharma P, Tripathi MK, Shrivastava SK. Cholinesterase as a Target for Drug Development in Alzheimer’s Disease. In: Labrou N. (eds) Targeting Enzymes for Pharmaceutical Development. Methods in Molecular Biology, vol 2089. Humana, New York, NY 2020.
  • Tripathi MK, Sinha J, Srivastava SK, Kumar D. Bioinformatics in Skin Cancer: A System Biology Approach to Understanding the Molecular Mechanisms and It’s Regulations. In: Dwivedi A., Agarwal N., Ray L., Tripathi A. (eds) Skin Aging & Cancer. Springer, Singapore 2019.
  • Kumar M, Sharma P, Maheshwari R, Tekade M, Shrivastava SK, Tekade RK. Beyond the Blood–Brain Barrier: Facing New Challenges and Prospects of Nanotechnology-Mediated Targeted Delivery to the Brain, Elsevier (Academic Press), 2018, pp. 397-437.
  • Das N, Sharma PA, Seth A, Maheshwari R, Shrivastava SK, Tekade RK, Chapter 5- An overview of dendrimers and its biomedical applications, Apple Academic Press, A CRC Press (Taylor & Francis) 2018.
  • Seth A, Sharma PA, Maheshwari R, Shrivastava SK, Tekade RK. Chapter 7- Dendrimers in targeted drug delivery, Apple Academic Press, A CRC Press (Taylor & Francis) 2018.
  • Sharma PA, Maheshwari R, Shrivastava SK, Tekade RK. Chapter 9- Dendrimers in gene delivery, Apple Academic Press, A CRC Press (Taylor & Francis), 2018.
  • Dhanawat M, Sharma GK, Shrivastava SK. The new heteroaryl compounds having 5-HT1A/5-HT2A affinity- Design, synthesis & evaluation of some new heteroaryl compounds having 5-HT1A/5-HT2A affinity and anticonvulsant activity, Lap Lambert Academic Publishing,2015, ISBN: 978-3-659-69488-2.

Ph.D Supervised-  15 
(1) Ms. Priyanka Kumari Choubey
(2) Ms. Mousumi Besan (Awarded)
(3) Mr. Avanish Tripathi (Awarded)
(4) Mr. Piyoosh Sharma (Awarded)
(5) Mr. Prabhash Nath Tripathi (Awarded)
(6) Mr. Pavan Srivastava (Awarded)
(7) Mr. Ankit Seth (Awarded)
(8) Mr. Anupam G. Banerjee (Awarded)
(9) Mr. Kamal Shah (Awarded)
(10) Mr. Nirupam Das (Awarded)
(11) Mr. Saurabh Kumar Sinha (Awarded)
(12) Ms. Shubhanjali Shukla (Awarded)
(13) Ms. Meenakshi Dhanawat (Awarded)
(14) Mr. Prabhat Kumar Shrivastava (Awarded)
(15) Mr. K.P. Namdeo (Awarded)

Ph.D. Supervision ongoing-                                              05 
(1) Mr. Digambar Kumar Waiker
(2) Ms. Poorvi Saraf
(3) Mr. Akash Verma
(4) Ms. Bhagwati Bharadwaj
(5) Mr. Hansal Paresh Kumar

M.Pharm Thesis Dissertation Supervised-                         32       
M.Pharm Thesis Dissertation supervision ongoing-           00

  • Coordinator training & placement cell IIT-BHU, Varanasi.
  • BoG Nominee from UGC at Seven Hills College of Pharmacy, Tirupati, Andhra Pradesh, India.
  • Illustrious Aluminous Award from “Dr. H.S. Gour Vishwavidyalaya, Department of Pharmaceutical Sciences, Sagar (M.P.)” 2016
  • Best Poster Award for the presentation entitled “Synthesis, evaluation and docking studies of some novel 1,2,4-triazine derivatives bearing five member heterocyclic moiety as potential anti-inflammatory and analgesic agents” in “Pharma Middle East - 2015” held from 02nd - 04th, November 2015 at Dubai, UAE.
  • Prof. S. B. Sonawane memorial award for the Best Paper in IJPER publication, 2012
  • Senior scientist award from “European Institute of Scientific Research on Ayurveda (EISRA)” 2015 Netherland
  • Best paper award - St. John’s Pharmacy College award for the Best Paper in Pharmaceutical Analysis. IJPR, 2009
  • St. John’s Pharmacy College Award for Best Paper in Pharmaceutical Analysis for the article entitled “Stress Stability Studies and the Estimation of Lamotrigine in Pharmaceutical Formulation by Validated RP-HPLC Method” organized by Indian Journal of Pharmaceutical Education and Research, APTI- 15Annual National Convention Hyderabad. (2-3 November 2010).
  • St. John’s Pharmacy College award for the Best Paper in Pharmaceutical Analysis. “Stress Stability Studies and Estimation of Lamotrigine in Pharmaceutical Formulation by validated RP-HPLC method” IJPR, 43, 2009,156-161.