Drug Development through Design and synthesis of new chemical entities & isolation of active constituents from Medicinal plants for major diseases/disorders of human by both conventional and advanced techniques

• Principal Investigator, Development of bioactive molecules as therapeutic agent for Alzheimer’s disease and screening their toxicity; IIT (BHU), Varanasi.
• Principal Investigator, Design and synthesis is of Matrix Metallo Proteinase (MMP -2 & 9) inhibitors as therapeutic agents for Alzheimer’s disease; DBT, New Delhi.
• Co- Principal Investigator, Cestocidal activity of glands and hairs of fruits of Mallotus phillippinensis (Kampillaka Plant); ICMR, New Delhi.
• Principal Investigator, Ethno-medicinal plants as a source of new therapeutic agents against psoriasis; National medicinal Plant Board, AYUSH, New Delhi.
• Principal Investigator, Isolation of marker compounds from Withania somnifera; Natreon Inc., Kolkata.
• Principal Investigator, Isolation of marker Compounds from natural Sources; Drug Research and Development Center, Kolkata.
• One of the Investigators of the Centre, Establishment of facilities for identification, chemical characterization, standardization and quality control of medicinal plants found in tribal area in central India; DST, New Delhi.

1. Ganeshpurkar A, Singh R, Shivhare S, Kumar D, Gutti G, Singh R, et al. Improved machine learning scoring functions for identification of Electrophorus electricus’s acetylcholinesterase inhibitors. Molecular Diversity. 2021:1-25.
2. Makar S, Ghosh A, Shivhare S, Kumar A, Singh SK. Molecular Processes Involved in Pancreatic Cancer and Therapeutics. Current Chemical Biology. 2021;15(1):85-108.
3. Bajad NG, Rayala S, Gutti G, Sharma A, Singh M, Kumar A, et al. Systematic review on role of structure based drug design (SBDD) in the identification of anti-viral leads against SARS-Cov-2. Current Research in Pharmacology and Drug Discovery. 2021;2:100026.
4. Firdaus Z, Singh SK, Singh TD, Singh M. The scientific community in COVID-19 global pandemic: A systematic update on recent progress and challenges. European Journal of Chemistry. 2021;12(2):222-34.
5. Makar S, Saha T, Swetha R, Gutti G, Kumar A, Singh SK. Rational approaches of drug design for the development of selective estrogen receptor modulators (SERMs), implicated in breast cancer. Bioorganic chemistry. 2020;94:103380.
6. Singh RB, Das N, Singh GK, Singh SK, Zaman K. Synthesis and pharmacological evaluation of 3-[5-(aryl-[1, 3, 4] oxadiazole-2-yl]-piperidine derivatives as anticonvulsant and antidepressant agents. Arabian Journal of Chemistry. 2020;13(5):5299-311.
7. Singh R, Ganeshpurkar A, Kumar D, Kumar D, Kumar A, Singh SK. Identifying potential GluN2B subunit containing N-Methyl-D-aspartate receptor inhibitors: An integrative in silico and molecular modeling approach. Journal of Biomolecular Structure and Dynamics. 2020;38(9):2533-45.
8. T.S. John. P.K. Yadav DK, S.K. Singh, Hasan SH. Highly fluorescent carbon dots from wheat bran as a novel drug delivery system for bacterial inhibition. Luminescence. 2020;35(6):913-23.
9. S. Siddamurthi GG, S. Jana, Ashok Kumar, Singh SK. Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy. Future Medicinal Chemistry. 2020;12(11):1037-69.
10. Ganeshpurkar A, Makar S, Kumar D, Jana S, Singh SK. Aspartic proteases: Potential drug targets for anticancer drug development.  Cancer-Leading Proteases: Academic Press; 2020. p. 121-63.
11. Makar S, Ghosh A, Kumar A, Singh SK. Recent Studies on Aromatase and Sulfatase Involved in Breast Cancer and their Inhibitors. Current Enzyme Inhibition. 2020;16(1):20-44.
12. Ganeshpurkar A, Singh R, Gore PG, Kumar D, Gutti G, Kumar A, et al. Structure-based screening and molecular dynamics simulation studies for the identification of potential acetylcholinesterase inhibitors. Molecular Simulation. 2020;46(3):169-85.
13. Ganeshpurkar A, Singh R, Kumar D, Divya, Shivhare S, Kumar A, et al. Computational binding study with α7 nicotinic acetylcholine receptor of Anvylic-3288: an allosteric modulator. Molecular Simulation. 2020;46(13):975-86.
14. Modi A, Singh M, Gutti G, Shanker OR, Singh VK, Singh S, et al. Benzothiazole derivative bearing amide moiety induces p53-mediated apoptosis in HPV16 positive cervical cancer cells. Investigational new drugs. 2020;38(4):934-45.
15. Gutti G, Kumar D, Paliwal P, Ganeshpurkar A, Lahre K, Kumar A, et al. Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer’s disease. Bioorganic chemistry. 2019;90:103080.
16. Gutti G, Kakarla R, Kumar D, Beohar M, Ganeshpurkar A, Kumar A, et al. Discovery of novel series of 2-substituted benzo [d] oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease. European journal of medicinal chemistry. 2019;182:111613.
17. Gutti G, Arya K, Singh SK. Latent tuberculosis infection (LTBI) and its potential targets: An investigation into dormant phase pathogens. Mini reviews in medicinal chemistry. 2019;19(19):1627-42.
18. Jana S, Singh SK. Identification of selective MMP-9 inhibitors through multiple e-pharmacophore, ligand-based pharmacophore, molecular docking, and density functional theory approaches. Journal of Biomolecular Structure and Dynamics. 2019;37(4):944-65.
19. Saha T, Makar S, Swetha R, Gutti G, Singh SK. Estrogen signaling: An emanating therapeutic target for breast cancer treatment. European journal of medicinal chemistry. 2019;177:116-43.
20. Jana S, Singh SK. Identification of human tau-tubulin kinase 1 inhibitors: An integrated e-pharmacophore-based virtual screening and molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics. 2019.
21. Ganeshpurkar A, Gutti G, Singh SK. RNA-dependent RNA polymerases and their emerging roles in antiviral therapy.  Viral Polymerases: Academic Press; 2019. p. 1-42.
22. Kumar D, Gupta SK, Ganeshpurkar A, Singh R, Kumar D, Das N, et al. Biological profiling of piperazinediones for the management of anxiety. Pharmacology Biochemistry and Behavior. 2019;176:63-71.
23. Mahapatra DK, Bharti SK, Asati V, Singh SK. Perspectives of medicinally privileged chalcone based metal coordination compounds for biomedical applications. European journal of medicinal chemistry. 2019;174:142-58.
24. Makar S, Saha T, Singh SK. Naphthalene, a versatile platform in medicinal chemistry: Sky-high perspective. European journal of medicinal chemistry. 2019;161:252-76.
25. Sellamuthu S, Bhat MF, Kumar A, Nath G, Singh SK. Design, Synthesis and Biological Evaluation of Carbazole Derivatives as Antitubercular and Antibacterial Agents. Current Bioactive Compounds. 2019;15(1):83-97.
26. Ganeshpurkar A, Swetha R, Kumar D, Gangaram GP, Singh R, Gutti G, et al. Protein-protein interactions and aggregation inhibitors in Alzheimer’s disease. Current topics in medicinal chemistry. 2019;19(7):501-33.
27. Swetha R, Kumar D, Gupta SK, Ganeshpurkar A, Singh R, Gutti G, et al. Multifunctional hybrid sulfonamides as novel therapeutic agents for Alzheimer’s disease. Future medicinal chemistry. 2019;11(24):3161-78.
28. Singh SK, Nath G, Kumar A, Sellamuthu SK. Design, Synthesis and Biological Profiling of Novel Phenothiazine Derivatives as Potent Antitubercular Agents. Anti-Infective Agents. 2019;17(1):50-65.
29. Sellamuthu S, Kumar A, Nath G, Singh SK. Design, Synthesis and Biological Profiling of Novel Phenothiazine Derivatives as Potent Antitubercular Agents. 2018.
30. Ganeshpurkar A, Kumar D, Singh SK. Design, synthesis and collagenase inhibitory activity of some novel phenylglycine derivatives as metalloproteinase inhibitors. International journal of biological macromolecules. 2018;107:1491-500.
31. Jana S, Ganeshpurkar A, Singh SK. Multiple 3D-QSAR modeling, e-pharmacophore, molecular docking, and in vitro study to explore novel AChE inhibitors. RSC advances. 2018;8(69):39477-95.
32. Ganeshpurkar A, Kumar D, Singh SK. Strategies for the synthesis of Hydroxamic Acids. Current Organic Synthesis. 2018;15(2):154-65.
33. Sellamuthu S, Asseri AH, Goojani HG, Nath G, Singh SK. Preliminary studies on ligand-based design and evaluation of new mycobacterial ATP synthase inhibitors. Current Drug Therapy. 2018;13(1):56-73.
34. Singh RB, Singh GK, Chaturvedi K, Kumar D, Singh SK, Zaman MK. Design, synthesis, characterization, and molecular modeling studies of novel oxadiazole derivatives of nipecotic acid as potential anticonvulsant and antidepressant agents. Medicinal Chemistry Research. 2018;27(1):137-52.
35. Kumar D, Ganeshpurkar A, Kumar D, Modi G, Gupta SK, Singh SK. Secretase inhibitors for the treatment of Alzheimer's disease: Long road ahead. European journal of medicinal chemistry. 2018;148:436-52.
36. Kumar D, Gupta SK, Ganeshpurkar A, Gutti G, Krishnamurthy S, Modi G, et al. Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease. European journal of medicinal chemistry. 2018;150:87-101.
37. Sellamuthu S, Gutti G, Kumar D, Kumar Singh S. Carbazole: A Potent Scaffold for Antitubercular Drugs. Mini-Reviews in Organic Chemistry. 2018;15(6):498-507.
38. Sellamuthu S, Bhat MF, Kumar A, Singh SK. Phenothiazine: A better scaffold against tuberculosis. Mini reviews in medicinal chemistry. 2018;18(17):1442-51.
39. Swetha R, Gayen C, Kumar D, Singh TD, Modi G, Singh SK. Biomolecular basis of matrix metallo proteinase-9 activity. Future medicinal chemistry. 2018;10(9):1093-112.
40. Singh SK, Dutta A, Modi G. α-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinson's disease. Future medicinal chemistry. 2017;9(10):1039-53.
41. Sellamuthu S, Singh M, Kumar A, Singh SK. Type-II NADH Dehydrogenase (NDH-2): a promising therapeutic target for antitubercular and antibacterial drug discovery. Expert opinion on therapeutic targets. 2017;21(6):559-70.
42. Singh M, Kumar Singh S, Gangwar M, Sellamuthu S, Nath G, K Singh S. Design, synthesis and mode of action of some new 2-(4'-aminophenyl) benzothiazole derivatives as potent antimicrobial agents. Letters in Drug Design & Discovery. 2016;13(5):429-37.
43. Singh M, Modi A, Narayan G, Singh SK. Benzothiazole derivatives bearing amide moiety: potential cytotoxic and apoptosis-inducing agents against cervical cancer. Anti-cancer drugs. 2016;27(6):519-32.
44. Singh M, Singh SK, Gangwar M, Nath G, Singh SK. Design, synthesis and mode of action of novel 2-(4-aminophenyl) benzothiazole derivatives bearing semicarbazone and thiosemicarbazone moiety as potent antimicrobial agents. Medicinal Chemistry Research. 2016;25(2):263-82.
45. Singh M, Kumar Singh S, Thakur B, Ray P, K Singh S. Design and synthesis of novel Schiff base-benzothiazole hybrids as potential epidermal growth factor receptor (EGFR) inhibitors. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents). 2016;16(6):722-39.
46. Bharti SK, Mahapatra D, Singh SK. Thiazole: A Simple Scaffold with Tremendous Therapeutic Potential. Chemical and Biochemical Engineering: New Materials and Developed Components. 2015:43.
47. Singh SK, Chouhan HS, Sahu AN, Narayan G. Assessment of in vitro antipsoriatic activity of selected Indian medicinal plants. Pharmaceutical biology. 2015;53(9):1295-301.
48. Singh M, Gangwar M, Nath G, Singh SK. Synthesis, DNA cleavage and antimicrobial activity of 4-thiazolidinones-benzothiazole conjugates. 2014.
49. Bharti SK, Singh SK. Design, synthesis and biological evaluation of some novel benzylidene-2-(4-phenylthiazol-2-yl) hydrazines as potential anti-inflammatory agents. Medicinal Chemistry Research. 2014;23(2):1004-15.
50. Kumar P, Saxena A, Singh S, Agarwal S. Glycoproteins profiles of placental extract-A step towards development of biomarkers of pregnancy in water buffalo. Indian Journal of Animal Sciences. 2014;84:424-6.
51. Kumar D, BG H, Gangwar M, Kumar M, Kumar D, Tilak R, et al. Synthesis, molecular docking and in vitro antimicrobial studies of novel pyrazole analogues of curcumin. Letters in Drug Design & Discovery. 2014;11(4):474-83.
52. Singh M, Singh SK. Benzothiazoles: how relevant in cancer drug design strategy? Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents). 2014;14(1):127-46.
53. Singh M, Singh SK, Gangwar M, Nath G, Singh SK. Design, synthesis and mode of action of some benzothiazole derivatives bearing an amide moiety as antibacterial agents. RSC advances. 2014;4(36):19013-23.
54. Singh M, K Singh S, T Chhabria M, Vasu K, Pandya D. CoMFA and CoMSIA 3D QSAR Models for a Series of Some Condensed Thieno [2, 3-d] pyrimidin-4 (3H)-ones with Antihistaminic (H1) Activity. Medicinal Chemistry. 2013;9(3):389-401.
55. Jain P, Saravanan C, Singh SK. Sulphonamides: Deserving class as MMP inhibitors? European journal of medicinal chemistry. 2013;60:89-100.
56. Kumar D, Kumar M, Kumar A, Kumar Singh S. Chalcone and curcumin derivatives: a way ahead for malarial treatment. Mini reviews in medicinal chemistry. 2013;13(14):2116-33.
57. Gangwar M, Verma VC, Singh TD, Singh SK, Goel R, Nath G. In-vitro scolicidal activity of Mallotus philippinensis (Lam.) Muell Arg. fruit glandular hair extract against hydatid cyst Echinococcus granulosus. Asian Pacific Journal of Tropical Medicine. 2013;6(8):595-601.
58. Kumar D, BG H, Gangwar M, Kumar M, Kumar D, Nath G, et al. Synthesis, molecular docking and in vitro antimicrobial studies of new hexahydroindazole derivatives of curcumin. Letters in Drug Design & Discovery. 2013;10(2):119-28.
59. Saravanan C, Punitha AD, Srivastava AK, Nath G, Singh SK. Antibacterial activity of novel 2-(substituted sulfonamido) benzoic acid derivatives. Journal of Pharmacy Research. 2013;7(6):525-8.
60. Baithalu RK, Singh S, Gupta C, Raja AK, Saxena A, Kumar Y, et al. Cellular and functional characterization of buffalo (Bubalus bubalis) corpus luteum during the estrous cycle and pregnancy. Animal reproduction science. 2013;140(3-4):138-46.
61. Bhattamisra SK, Singh PN, Singh SK. Effect of standardized extract of Marsilea minuta on learning and memory performance in rat amnesic models. Pharmaceutical biology. 2012;50(6):766-72.
62. Kumar D, Kumar M, Saravanan C, Singh SK. Curcumin: a potential candidate for matrix metalloproteinase inhibitors. Expert opinion on therapeutic targets. 2012;16(10):959-72.
63. Gangwar M, Dalai A, Chaudhary A, Singh T, Singh SK, Goel R, et al. Study on activity of alcoholic extract of glands and hairs of fruits of Mallotus philippinensis in murine cestodal infection model. Int J Pharm Pharm Sci. 2012;4(Suppl 1):643-5.
64. Chouhan HS, Sridevi K, Singh NK, Singh SK. Anti-inflammatory activity of ethanol extract of Vitex glabrata leaves. Pak J Pharm Sci. 2012;25(1):131-4.
65. Singh M, Singh SK, Chhabria MT. A novel QSAR model for evaluating and predicting the inhibition activity of H1-receptor antagonists: a series of thienopyrimidine derivatives. Journal of Drug Delivery and Therapeutics. 2012;2(1).
66. Sridevi V, Chouhan HS, Singh NK, Singh SK. Antioxidant and hepatoprotective effects of ethanol extract of Vitex glabrata on carbon tetrachloride-induced liver damage in rats. Natural product research. 2012;26(12):1135-40.
67. Saravanan C, Singh SK. Status of research on MMPs in India. Expert opinion on therapeutic targets. 2011;15(6):715-28.
68. Chouhan HS, Singh SK. Phytochemical analysis, antioxidant and anti-inflammatory activities of Phyllanthus simplex. Journal of Ethnopharmacology. 2011;137(3):1337-44.
69. Chouhan HS, Singh SK. A review of plants of genus Leucas. Journal of Pharmacognosy and Phytotherapy. 2011;3(2):13-26.
70. Chouhan HS, Sahu AN, Singh SK. Fatty acid composition, antioxidant, anti-inflammatory and antibacterial activities of seed oil from Crotalaria juncea Linn. Journal of Medicinal Plants Research. 2011;5(6):984-91.
71. Gangwar M, Kumar D, Tilak R, Singh TD, Singh SK, Goel R, et al. Qualitative phytochemical characterization and antibacterial evaluation of glandular hairs covering of Mallotus phillippinensis fruit extract. J Pharma Res. 2011;4:4214-6.
72. Chouhan HS, Singh SK. Synthesis and characterization of some Mannich bases as potential antimicrobial agents. Asian Journal of Chemistry. 2010;22(10):7903.
73. Chouhan H, Bharti S, Singh S. 2D-Quantitative Structure Property Relationship Study of N-(Aryl)-2-thiophene-2-ylacetamide Derivatives as Antitubercular Agents. Asian Journal of Chemistry. 2010;22(6):4675.
74. Bharti S, Nath G, Tilak R, Singh S. Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2, 4-disubstituted thiazole ring. European journal of medicinal chemistry. 2010;45(2):651-60.
75. Bharti SK, Patel SK, Nath G, Tilak R, Singh SK. Synthesis, characterization, DNA cleavage and in vitro antimicrobial activities of copper (II) complexes of Schiff bases containing a 2, 4-disubstituted thiazole. Transition Metal Chemistry. 2010;35(8):917-25.
76. Chouhan H, Singh SK. ANTIBACTERIAL ACTIVITY OF PHYLLANTUS SIMPLEX LINN. Pharmacologyonline; 2010.
77. Chouhan HS, Singh SK. Antibacterial activity of seed and flower parts of Crotalaria juncea Linn. American-Eurasian Journal of Scientific Research. 2010;5(3):212-5.
78. Bharti SK, Singh SK. Recent developments in the field of anticancer metallopharmaceuticals. International Journal of PharmTech Research. 2009;1(4):1406-20.
79. Singh S, Prabha T, Kavitha B, Chouhan H, Bharti S. Anti-inflammatory and hepatoprotective activities of ethanolic extract of Euphorbia thymifolia Linn. Pharmacologyonline. 2009;1:986-94.
80. Jasemine S, Srivastava R, Singh S. Antidiabetic and antioxidant effect of various fractions of Phyllanthus simplex in alloxan diabetic rats. Journal of Ethnopharmacology. 2009;124(1):34-8.
81. Bharti SK, Singh SK. Metal based drugs: Current use and future potential. Der Pharmacia Lettre. 2009;1(2):39-51.
82. Shabeer J, Srivastava RS, Singh SK. Antidiabetic and antioxidant effect of various fractions of Phyllanthus simplex in alloxan diabetic rats. Journal of Ethnopharmacology. 2009;124(1):34-8.
83. Bhattamisra SK, Khanna VK, Agrawal AK, Singh PN, Singh SK. Antidepressant activity of standardised extract of Marsilea minuta Linn. Journal of ethnopharmacology. 2008;117(1):51-7.
84. Jasemine S, Srivastava RS, Singh SK. Hepatoprotective Effect of Crude Extract and Isolated Lignans of Justicia simplex. against CCl4-Induced Hepatotoxicity. Pharmaceutical biology. 2007;45(4):274-7.
85. Bhattamisra S, Singh P, Singh S, Kumar V. Anxiolytic activity of Marsilea minuta Linn in rodents. Journal of Herbal Medicine and Toxicology. 2007;1(1):15-20.
86. Bhattamisra S, Singh P, Singh S. Behavioural characterization of Marsilea minuta in rodents. Indian J Nat Prod. 2006;22:3-7.
87. Balasundari P, Singh S, Kavimani S. Free radical scavenging of xanthones from Swertia chirata Buchham and tumor cell growth inhibition. Main Group Chemistry. 2005;4(3):177-85.
88. Bhasin P, SACHDEVA N, Pandeya S, Nath G, Singh S. Synthesis and evaluation of Schiff and N-Mannich bases of isatin as potential antimicrobial agents. ACTA Pharmaceutica Sciencia. 2005;47(1).
89. Amir M, Kumar S, Singh S. Chemical and biological review of Phyllanthus niruri. Natural Product Updates. 2004;19(4):3-13.
90. Kumar K, Singh S, Pandeya S. Synthesis and antibacterial activity of pyridyl thioureas and arylthiosemicarbazones. Bollettino chimico farmaceutico. 2001;140(4):238-42.
91. Singh S, Tuli L, SINGH V, Prithiviraj B. Effect of temperature, light/darkness and relative humidity on germination and sporulation of Alternaria tenuissima. Indian Phytopathology. 2001;54(1):128-30.
92. Tripathi D, Sharma N, Singh S, Gupta LK. Identification of bovine sperm specific polypeptides reactive with antisperm antibodies. 1999.
93. Ghosal S, Sundaram R, Muruganandam A, Singh S, Satyan K, Bhattacharya S, et al. The chemistry and action of 6-alkylsalicylates of Indian Ginkgo biloba. 1997.
94. Ghosal S, Lal J, Singh SK. The core structure of Shilajit humus. Soil Biology and Biochemistry. 1991;23(7):673-80.
95. GHOSAL S, DATTA K, Singh S, KUMAR Y. Significance of Amaryllidaceae alkaloids in a unique plant-insect interaction. Indian journal of chemistry Sect B: Organic chemistry, including medical chemistry. 1991;30(2):260-4.
96. Ghosal S, Lal J, Singh SK, Goel RK, Jaiswal AK, Bhattacharya SK. The need for formulation of Shilajit by its isolated active constituents. Phytotherapy research. 1991;5(5):211-6.
97. GHOSAL S, DATTA K, Singh S, KUMAR Y. Telastaside, a stress-related alkaloid-conjugate from Polytela gloriosa, an insect feeding on Amaryllidaceae. Journal of chemical research Synopses (Print). 1990(10):334-5.
98. Ghosal S, Singh SK, Unnikrishnan SG. Effects of stress on alkaloid metabolism in Crinum asiaticum. Phytochemistry. 1990;29(3):805-11.
99. GHOSAL S, LAL J, SINGH SK, KUMAR Y, SOTI F. Shilajit. IV: Chemistry of two bioactive benzopyrone metabolites. Journal of chemical research Synopses (Print). 1989(11):350-1.
100. Ghosal S, Lal J, Singh SK, Dasgupta G, Bhaduri J, Mukhopadhyay M, et al. Mast cell protecting effects of shilajit and its constituents. Phytotherapy Research. 1989;3(6):249-52.
101. GHOSAL S, Singh SK, Battacharya S. Mangicrocin, an adaptogenic xanthone-carotenoid glycosidic conjugate from saffron. Journal of chemical research Synopses (Print). 1989(3):70-1.
102. Ghosal S, Unnikrishnan S, Singh SK. Occurrence of two epimeric alkaloids and metabolism compared with lycorine in Crinum latifolium. Phytochemistry. 1989;28(9):2535-7.
103. Ghosal S, Mittal P, Kumar Y, Singh SK. Free and glucosyloxy acetophenones from Pancratium biflorum. Phytochemistry. 1989;28(11):3193-6.
104. Ghosal S, Singh SK, Kumar Y, Unnikrishnan S, Chattopadhyay S. The role of ungeremine in the growth-inhibiting and cytotoxic effects of lycorine: evidence and speculation. Planta medica. 1988;54(02):114-6.
105. Ghosal S, Singh SK, Kumar Y, Srivastava R, Goel RK, Dey R, et al. Anti‐ulcerogenic activity of fulvic acids and 4′‐methoxy‐6‐carbomethoxybiphenyl isolated from shilajit. Phytotherapy Research. 1988;2(4):187-91.
106. GHOSAL S, Singh S, Srivastava R. Shilajit. II: Biphenyl metabolites from Trifolium repens. Journal of chemical research Synopses (Print). 1988(6):196-7.
107. Ghosal S, Singh S, Kumar Y, Srivastava R, Goel R, Dey R, et al. Shilajit. 3. Antiulcerogenic of fulvic acids and 4-methoxy-6-carbomethoxybiphenyl isolated from shilaji. Phytotherapy Research. 1988;2(4):187-91.
108. Srivastava R, Kumar Y, Singh S, Ghosal S, editors. Shilajit, its source and active principles. Proc; 1988.
109. Ghosal S, Shanthy A, Singh SK. Isocraugsodine, an n-arylidenephenethylamine from Crinum asiaticum and its ez isomerism. Phytochemistry. 1988;27(6):1849-52.
110. Ghosal S, Singh SK, Unnikrishnan SG. Phosphatidylpyrrolophenanthridine alkaloids from Zephyranthes flava. Phytochemistry. 1987;26(3):823-8.
111. Ghosal S, Singh SK, Srivastava RS. Alkaloids of Zephyranthes flava. Phytochemistry. 1986;25(8):1975-8.
112. Ghosal S, Kumar Y, Chakrabarti DK, Lal J, Singh SK. Parasitism of Imperata cylindrica on Pancratium biflorum and the concomitant chemical changes in the host species. Phytochemistry. 1986;25(5):1097-102.
113. Ghosal S, Kumar Y, Singh S, Shanthy A. Chemical constituents of amaryllidaceae. XIX: The occurrence of N-(3-hydroxy-4-methoxybenzylidene)-4'-hydroxyphenethylamine in Crinum augustum and its biogenetic significance. Journal of chemical research Synopses (Print). 1986(1):28-9.
114. GHOSAL S, KUMAR Y, Singh S, KUMAR A. Chemical constituents of Amaryllidaceae. XXI: Ungeremine and criasbetaiene, two anti-tumour alkaloids from Crinum asiaticum. Journal of chemical research Synopses (Print). 1986(3):112-3.
115. GHOSAL S, Singh S. Chemical constituents of amaryllidaceae. XXIV: Crinafoline and crinafolidine, two anti-tumour alkaloids from Crinum latifolium. Journal of chemical research Synopses (Print). 1986(8):312-3.
116. Ghosal S, Singh SK, Srivastava RS. Flavans from Zephyranthes flava. Phytochemistry. 1985;24(1):151-3.
117. Ghosal S, Biswas K, Saini K, Singh S. REGIOSELECTIVE CLEAVAGE OF METHYLENEDIOXY RING IN XANTHONES: AN ENTRY INTO IMMUNO‐STIMULANT 7‐GLUCOSYLOXYPOLYMETHOXYXANTHONES. Chemischer Informationsdienst. 1985;16(21):no-no.
118. Ghosal S, Jaiswal DK, Singh SK, Srivastava RS. Dichotosin and dichotosinin, two adaptogenic glucosyloxy flavans from Hoppea dichotoma. Phytochemistry. 1985;24(4):831-3.
119. Singh M, Nath G, Singh SK. Design, synthesis and mode of action of some new amide derivatives of 2-(4′-aminophenyl) benzothiazole as potent antimicrobial agents.
120. Gangwar M, Verma V, Singh T, Singh S, Goel R, Nath G. In-vitro scolicidal activity of Mallotus philippinensis (Lam.) Muell Arg. fruit glandular hair extract against hydatid cyst Echinococcus granulosus. Asian Pac J Trop Med. 2013; 6: 595–601. S1995-7645 (13).60103-0.
121. Singh S, Prabha T, Kavitha B, Chouhan H, Bharti S. ANTIDEPRESSANT ACTIVITY OF ETHANOLIC EXTRACT OF EUPHORBIA THYMIFOLIA LINN. IN THE FORCED SWIMMING TEST IN RATS.

• Organizing secretary, Pharmaco-Therapeutics and Formulation Development (PTFD-2005), Varanasi.
• Joint Secretary and chairman Registration committee, 59th Indian Pharmaceutical Congress held at Varanasi during Dec 2007
• Organizing Chairman, Emerging Trends in Drug Discovery & Development(ETDDD-2018), Varanasi

1. Head, Department of Pharmaceutical Engineering & Technology, IIT(BHU) (2015-18)
2. Associate NCC Officer (ANO), 2 UPEME, NCC COY, IT BHU & Commissioned as Lieut, (1992-2013)
3. Chairman, Organizing Committee ETDDD-2018, Chairman, IT Cafeteria (2009-10)
4. President, Association of Pharmaceutical Teachers of India (APTI) UP (2008-11)
5. Vice-President, Association of Pharmaceutical Teachers of India (APTI) UP (2004-07)
6. Joint Secretary & Chairman, Registration Committee, 59^th IPC Varanasi (2007)
7. Vice-President, Pharmaceutical Society of BHU (2003-04 & 2004-05)
8. Editor-in-Chief ‘The Pharmstudent’ the official publication of the Pharmaceutical of BHU (2003-04)
9. Organizing Secretary PTFD-2005
10. Chairman, Games Sports Wing, IT Gymkhana (2004-05)
11. Chairman, Cultural Wing, IT Gymkhana for two consecutive terms (2002-03 & 2003-04)
12. Secretary, Teachers Association, BHU (2001)
13. U.G.C. Junior Research Fellowship (1982-84)
14. U.G.C. Senior Research Fellowship (1985-88)
15. U.P. Government Merit Scholarship (1973-77)
16. Life Member IPA, APTI and IPGA

Thailand, Malaysia, United Kingdom, Spain, Austria, Czech Republic, Germany, Netherlands, France, Hungary

• S. K. Singh, A. Kumar, A. Ganeshpurkar, D. Kumar, R. Singh, P. Gore, G. Gutti, Novel sulfonamide derivatives of para-amino benzoic acid as selective Butrylcholinesterase (BuChE) inhibitors for the treatment of Alzheimer’s disease. Application No. 201911044199, Date of filing: 31/10/2019.
• S. K. Singh, G. P. Modi, D. Kumar, S. Rayala, C. Gayen, A. Ganeshpurkar, A Pharmaceutical Composition of Sulfonamide derivatives for the Treatment of Alzheimer’s Disease, Application No. 201711041328, Publication Date: 22/12/2017.
• S. K. Singh, A. Kumar, D. Kumar, D. Kumar, G. Gutti, A. Ganeshpurkar, Novel Quinolinyl piperazine derivatives as dual inhibitors of β secretase (BACE1) and acetylcholine esterase (AChE) for the management of Alzheimer’s disease. Application No. 201911032481, Date of filing: 10/8/2019.
• S. K. Singh, A. Kumar, G. Gutti, A. Ganeshpurkar, D. Kumar, R. Singh, Multitarget-directed triazole bridged cycloaryl analogues for treatment of Alzheimer’s disease, Application No. 202011047641, Date of filing: 31/10/2020.

M Pharm Students: 40 (completed)
Ph D Students: 10 (completed); 05 (ongoing)